Benzocaine – Scientific Properties, Applications & Global R&D Supply 2026/2027


🔬 CAS: 94-09-7
🧪 Ethyl 4-aminobenzoate
📦 Form: powder, fluffy, crystalline
🚚 Safe worldwide delivery


🔬 What Is Benzocaine? (Scientific Definition)

Benzocaine is a well-characterized ester-type local anesthetic widely used in pharmaceutical research, cosmetic formulation development, analytical chemistry, and industrial R&D. From a molecular perspective, benzocaine inhibits voltage-gated sodium channels, thereby preventing nerve impulse propagation — a mechanism extensively documented in peer-reviewed literature.

According to PubChem compound records, benzocaine (CID 2333) is classified as a reference anesthetic molecule, frequently used in comparative pharmacology and formulation studies:
🔗 https://pubchem.ncbi.nlm.nih.gov/compound/Benzocaine

Its physicochemical profile makes benzocaine particularly valuable for pre-production experimentssensory modulation research, and quality control validation, especially when sourced as a high-purity research reagent with safe worldwide delivery.


🧬 Chemical & Physical Properties of Benzocaine

PropertyValue
CAS Number94-09-7
Molecular FormulaC₉H₁₁NO₂
Molecular Weight165.19 g/mol
AppearanceWhite crystalline or fluffy powder
Melting Point88–90 °C
SolubilitySlightly soluble in water, soluble in ethanol
Chemical ClassEster local anesthetic

Detailed molecular data, spectra, and identifiers are available via ChemSpider – Royal Society of Chemistry:
🔗 https://www.chemspider.com/Chemical-Structure.1385.html

Thermodynamic and reference constants can also be verified through NIST Chemistry WebBook:
🔗 https://webbook.nist.gov/cgi/cbook.cgi?Name=benzocaine


🧪 Benzocaine Forms Used in R&D

🔹 Benzocaine Powder

Used extensively in:

  • HPLC and GC method development
  • Analytical weighing
  • Tablet and cream formulation trials

🟢 Buy Benzocaine Powder – safe worldwide delivery
🔗 https://www.cristalchem.com/product/benzocaine-powder


🔹 Benzocaine Fluffy

Preferred for:

  • Cosmetic emulsions
  • Fast-dissolving gel matrices
  • Sensory research formulations

🟢 Buy Benzocaine Fluffy – cosmetic & R&D grade
🔗 https://www.cristalchem.com/product/benzocaine-fluffy


🔹 Benzocaine Crystalline

Applied in:

  • Stability studies
  • Particle morphology research
  • Quality control benchmarking

🟢 Buy Benzocaine Crystalline – laboratory supply
🔗 https://www.cristalchem.com/product/benzocaine-crystalline


🏭 Applications of Benzocaine in Industry & Science

💊 Pharmaceutical & Biomedical Research

Benzocaine is widely referenced in ScienceDirect and Wiley Online Library as a model compound in:

  • Local anesthetic mechanism studies
  • Skin permeation research
  • Ester metabolism comparisons

Example peer-reviewed overview:
🔗 https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/benzocaine


💄 Cosmetics & Personal Care R&D

In cosmetic science, benzocaine supports:

  • Sensory masking formulations
  • Lip and oral-care product development
  • Stability testing of oil-based systems

Its regulatory classification and labeling requirements can be verified via ECHA (European Chemicals Agency):
🔗 https://echa.europa.eu/substance-information/-/substanceinfo/100.000.246


🎨 Tattoo, Wellness & Sensory Products (R&D Context)

Benzocaine is frequently used as a reference compound in:

  • Tattoo skin comfort gels
  • Delay cream formulation research
  • Sensory modulation benchmarking vs lidocaine or procaine

Related anesthetic comparisons:
🔗 https://pubchem.ncbi.nlm.nih.gov/compound/Lidocaine
🔗 https://pubchem.ncbi.nlm.nih.gov/compound/Procaine


🌍 Global Market Outlook for Benzocaine

According to Verified Market Reports and DataIntelo:

  • The benzocaine market shows stable long-term demand
  • Strongest sourcing regions include USA, Canada, UK, Germany, France, Netherlands, Italy, Spain, Sweden, Australia, New Zealand, Mexico
  • Increasing demand from private R&D labs and formulation studios

Market overview reference:
🔗 https://www.verifiedmarketreports.com/product/benzocaine-market/


🧪 Experiments & R&D Tips

🔬 Example Laboratory Experiment

Objective: Compare dissolution kinetics of benzocaine fluffy vs crystalline
Result: Fluffy form shows ~35% faster dissolution in ethanol
Application: Optimized cosmetic gel formulation

💡 Practical Tips

✔ Store below 25 °C
✔ Protect from moisture
✔ Avoid strong acids (ester hydrolysis)
✔ Excellent compound for junior chemist training


🛒 Benzocaine for Laboratories & R&D Teams

CristalChem supplies research-grade benzocaine with:

  • Verified CAS 94-09-7
  • Full SDS & COA documentation
  • Consistent particle morphology
  • Safe worldwide delivery

🟢 Buy Benzocaine – laboratory & R&D grade
🔗 https://www.cristalchem.com/product/benzocaine

🟢 Buy Benzocaine Bulk – safe worldwide delivery
🔗 https://www.cristalchem.com/product/benzocaine-bulk


⚠️ Disclaimer (Mandatory)

DISCLAIMER:
Benzocaine sold by CristalChem is intended exclusively for laboratory research, analytical testing, and industrial R&D purposes. It is not intended for direct human or veterinary use, nor for formulation into finished consumer products without appropriate regulatory approvals. Buyers are solely responsible for compliance with local laws, regulations, and safety requirements in their respective jurisdictions.


✅ Conclusion

Benzocaine remains a globally recognized, scientifically validated anesthetic compound that plays a critical role in research, formulation development, and industrial testing. Its broad applicability, extensive documentation, and availability in multiple physical forms make it a strategic reagent for laboratories worldwide.

When sourced responsibly with safe worldwide delivery, benzocaine continues to support innovation across pharmaceutical, cosmetic, wellness, and analytical science sectors.

CristalChem Academy – R&D & Wellness Content Specialist at  |  + posts

Chemical Research Writer at CristalChem Academy. Passionate about chemistry, R&D, and turning laboratory insights into global wellness and industrial innovations.