Description
🧪 Levamisole HCl (CAS 16595-80-5) – CristalChem
⚗️ Physical and Chemical Properties of Levamisole HCl
| Parameter | Value / Description |
|---|---|
| Form | Solid crystalline powder |
| Color | White to off-white |
| Odor | Odorless |
| Molar mass | 240.75 g/mol (Levamisole base: 204.3 g/mol) |
| Melting point | 257–259 °C (decomposes) |
| Density | ~1.44 g/cm³ |
| Solubility in water | Freely soluble |
| Solubility in organic solvents | Soluble in ethanol and methanol |
⚠️ Warnings
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H301: Toxic if swallowed.
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H315: Causes skin irritation.
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H319: Causes serious eye irritation.
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H335: May cause respiratory irritation.
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P260: Do not breathe dust.
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P280: Wear protective gloves and eye protection.
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P301 + P310: If swallowed, immediately contact a poison center or doctor.
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P305 + P351 + P338: If in eyes, rinse cautiously with water for several minutes.
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P501: Dispose of contents and containers according to local regulations.
Storage: Keep tightly sealed in a cool, dry, and ventilated area. Protect from sunlight and moisture.
For laboratory research and R&D use only. Not for human or veterinary use.
🔬 Mechanism of Action
Levamisole is an imidazothiazole derivative that acts as both an immunomodulator and an anthelmintic compound. It interferes with neuromuscular transmission in parasites, causing paralysis and allowing worms to be expelled from the host.
In mammals, researchers study Levamisole HCl for its ability to modulate the immune response. Consequently, it has become a model compound in research on oncology, autoimmune disorders, and immune stimulation.
💊 Main Uses of Levamisole HCl
1️⃣ Veterinary Medicine
Levamisole HCl plays a key role in veterinary parasitology.
It is widely used to control gastrointestinal and pulmonary nematodes in livestock, including sheep, cattle, goats, and pigs.
Moreover, it appears in formulations for deworming and parasite control, offering consistent efficacy across species.
2️⃣ Human Medicine (Historical and Research Context)
Historically, scientists investigated Levamisole HCl as an anthelmintic drug against roundworm infections in humans.
In addition, it served as a model in cancer adjuvant therapy (notably in colon cancer and melanoma studies).
Research into autoimmune disorders—such as rheumatoid arthritis—also showed promise, although long-term safety concerns limited its medical use.
Today, Levamisole’s pharmacological profile continues to support academic and toxicological research focused on immune modulation and cellular metabolism.
3️⃣ Aquaculture Research
In aquaculture, Levamisole HCl helps researchers study fish deworming, disease resistance, and immune stimulation.
Because of its defined activity, it remains a valuable tool for evaluating parasite control methods in aquatic environments.
4️⃣ Scientific and Industrial R&D
Laboratories use Levamisole HCl as a reference standard in chromatography, spectroscopy, and pharmacological studies.
Furthermore, it supports toxicological testing and resistance modeling in veterinary pharmacology.
Therefore, it continues to serve as a bridge between laboratory-scale experiments and industrial formulation design.
💧 Solubility and Laboratory Handling
Levamisole HCl dissolves easily in water, ethanol, and methanol, which makes it simple to prepare for experimental applications.
This excellent solubility ensures accurate dosing and uniform distribution in in vitro and in vivo systems.
When handled properly, the compound remains stable and reliable for long-term R&D work.
🌍 Levamisole HCl in Global Research
Because of its clear mechanism and reproducible results, Levamisole HCl remains an important reference compound for immunological and anthelmintic studies.
Research institutions around the world continue to use it to understand host–parasite interactions, test immune responses, and explore drug resistance models.
At CristalChem, we supply high-purity Levamisole HCl (CAS 16595-80-5) in laboratory-grade packaging for research and industrial applications.
We serve partners in England, Ireland, Scotland, Canada, Australia, Spain, New Zealand, Latvia, Sweden, Germany, Belgium, France, the Netherlands – and worldwide.
Because we ensure fast logistics, certified quality, and professional support, CristalChem is recognized as a trusted supplier for laboratories, universities, and R&D centers around the globe.
For laboratory and R&D use only. Not for human or veterinary use.




