Description
⚗️ Physical and Chemical Properties of Lidocaine HCl
Form: Solid
Chemical Formula: C₁₄H₂₂N₂O
Color: White
Odor: Odorless
Molar Mass: 288.8 g/mol
pH: 4.5–5 (in water, 5g/L at 20°C)
⚠️ Warnings
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H302: Harmful if swallowed — rinse mouth and drink plenty of water.
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P264: Wash thoroughly after handling.
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P270: Do not eat, drink, or smoke while handling the product.
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P301+P312: If swallowed: contact a poison center or doctor if you feel unwell.
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P330: Rinse mouth.
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P501: Dispose of contents/container in accordance with regulations.
Storage: Keep in a dry, cool place, tightly sealed, and away from sunlight.
All information below is intended for research and scientific purposes. The product is for professional laboratory use only.
💊 Overview of Lidocaine HCl
Lidocaine HCl is an amide-type local anesthetic widely used in research and laboratory testing. Because of its clear mechanism of action, stability, and reproducible results, it remains one of the most studied compounds in both academic and industrial R&D.
Researchers study lidocaine to understand nerve conduction, pain transmission, and anesthetic mechanisms. Its properties also make it suitable for developing new anesthetic analogs and studying molecular interactions at sodium channels.
🔬 Mechanism of Action
Lidocaine works by blocking sodium channels located in nerve cell membranes. As a result, it prevents the inflow of sodium ions and stops depolarization of the membrane.
Consequently, the nerve cannot transmit impulses to the brain, which leads to temporary loss of sensation and reduced pain perception.
This process occurs locally, in the specific area of application, and the effect usually lasts between 30 and 60 minutes, depending on dosage and surface contact.
Because of its precise action, researchers use lidocaine in experiments involving neural signaling, anesthetic modeling,and molecular pharmacology.
🧪 Applications and Research Uses
Lidocaine HCl is essential in several research areas:
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Anesthesiology: modeling of local anesthetic behavior,
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Dentistry and oral research: studies of topical pain relief and nerve desensitization,
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Pharmacology: analysis of sodium-channel blockade,
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Toxicology: exploration of metabolism and systemic effects,
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Biotechnology: development of nerve signal studies and bioactive formulations.
In each of these fields, lidocaine helps scientists better understand how the body processes anesthetic molecules and how nerve function can be regulated.
💧 Lidocaine Spray
Lidocaine spray provides a fast and direct way to deliver local anesthetic action. Researchers studying aerosol delivery systems often use spray formulations to test diffusion and onset of effect.
When applied in laboratory conditions, the vaporized compound interacts quickly with tissue models or test membranes.
This helps scientists evaluate bioavailability, penetration speed, and local stability of anesthetic compounds.
🧴 Lidocaine Gel
Lidocaine gels are used to study surface anesthesia and absorption kinetics. When applied to the skin or mucous membranes, they provide temporary numbing.
Researchers monitor onset time, duration, and concentration dependence to evaluate the compound’s effectiveness.
Moreover, gels are convenient for experiments that analyze pain models, dermatological absorption, and diffusion through biological membranes.
Typically, the anesthetic effect lasts 30–60 minutes, depending on dose and exposure surface.
🧤 Safety and Laboratory Practice
Always use personal protective equipment (PPE) when working with lidocaine HCl.
Avoid contact with eyes or skin and prevent inhalation of dust or vapors.
Store securely in a dry, cool, and well-ventilated space.
Following standard safety rules ensures consistent experimental results and product stability.
🌍 Lidocaine HCl at CristalChem
At CristalChem.com, researchers can order Lidocaine HCl (CAS 73-78-9) of certified high purity, packed in aluminum doypack bags that protect against light and humidity.
Each batch comes from verified suppliers and meets strict quality standards for laboratory and R&D use.
We deliver to laboratories, universities, and research institutions across England, Ireland, Scotland, Canada, Australia, Spain, New Zealand, Latvia, Sweden, Germany, Belgium, France, and the Netherlands — and worldwide.
Because of our reliable logistics and professional service, CristalChem is recognized as a trusted supplier of chemical reagents for research and development globally.
For laboratory and R&D use only. Not for human or veterinary use.









