Description
⚗️ Procaine HCL Fluffy (CAS 51-05-8) – CristalChem
🧪 Physico-chemical Properties of Procaine HCL
| Parameter | Value / Description |
|---|---|
| Chemical formula | C₁₃H₂₀N₂O₂ |
| CAS number | 51-05-8 |
| EC number | 200-077-2 |
| Molecular weight | 272.77 g/mol |
| Form | Crystalline powder |
| Color | White |
| Odor | Odorless |
⚠️ Safety and Handling
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H319: Causes serious eye irritation.
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H335: May cause respiratory irritation.
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H301: Toxic if swallowed.
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H315: Causes skin irritation.
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P301 + P310: If swallowed: immediately call a POISON CENTER or doctor.
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P261: Avoid breathing dust.
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P302 + P352: If on skin: wash with plenty of soap and water.
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P305 + P351 + P338: If in eyes: rinse carefully with water for several minutes.
Storage: Keep in a cool, dry place, in tightly closed containers. Protect from sunlight. Keep away from children.
📄 Consult the MSDS for complete safety and handling information.
💉 What Is Procaine HCL Fluffy?
Procaine hydrochloride (Procaine HCL) is an ester of p-aminobenzoic acid and N,N-diethylaminoethanol. It belongs to the class of local anesthetics and is known for its ability to block nerve conduction, providing temporary loss of sensation in targeted areas.
🧬 How Does Procaine HCL Work?
Procaine acts by blocking voltage-gated sodium channels in the nerve cell membrane.
As a result, it prevents the influx of sodium ions, stopping the generation and transmission of nerve impulses.
Therefore, the area treated with procaine becomes desensitized, reducing or completely eliminating pain sensations.
In medical practice, Procaine HCL is used mainly for local, spinal, and infiltration anesthesia.
However, it is not suitable for surface anesthesia because it does not absorb well through mucous membranes.
💊 Applications of Procaine HCL Fluffy
Medical use
Procaine HCL is used to anesthetize the skin, mucous membranes, soft tissues, and joints during:
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blood sampling and venipuncture,
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mole or lesion removal,
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dental fillings and root canal treatments,
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minor surgical or dermatological procedures.
In analgesic therapy, procaine helps relieve rheumatic, muscular, and neuralgic pain as well as migraines.
When combined with benzylpenicillin, it reduces injection pain and extends the drug’s duration of action.
Veterinary use
Procaine is also used in veterinary medicine for anesthesia during minor animal procedures.
Scientific and analytical use
In laboratories, Procaine HCL functions as a chemical reagent in:
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electrophoresis,
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spectrophotometry,
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chromatography,
helping detect compounds and validate analytical methods.
⚡ Effects and Duration
The effects of Procaine HCL depend on the dose and method of administration.
Typically, subcutaneous or local injection produces anesthesia lasting several dozen minutes.
Some users experience mild tingling, while others achieve complete numbness of the treated area.
🔬 Role in Modern Research
Researchers continue to use Procaine HCL as a model compound in studies related to:
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neural conduction,
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ion channel pharmacology,
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comparative anesthetic research.
Because of its well-documented mechanism, Procaine HCL remains a key reference reagent in medical chemistry, toxicology, and biophysics.
For laboratory and R&D use only. Not for human or veterinary administration.







