Introduction
Benzocaine (CAS: 94-09-7) is a white crystalline powder and one of the earliest known ester-type anesthetics. In laboratories, it is valued as a chemical reagent for analytical, educational, and comparative purposes.
CristalChem supplies Benzocaine Fluffy & Mesh Powder – buy online with guaranteed safe worldwide delivery and full documentation (SDS, COA).
Physical & Chemical Properties
| Parameter | Value |
|---|---|
| Formula | C9H11NO2 |
| Molecular weight | 165.19 g/mol |
| CAS | 94-09-7 |
| Appearance | White crystalline powder (fluffy or mesh) |
| Melting point | 88–90 °C |
| Solubility | Soluble in ethanol and chloroform, sparingly in water |

Laboratory Applications of Benzocaine
- Analytical chemistry: reference material in HPLC, TLC and spectroscopy.
- Pharmacological research: model ester anesthetic used in R&D for structure–activity studies.
- Education: teaching crystallisation, solubility, and melting point determination.
- Comparative studies: examined alongside Lidocaine HCL – research reagent and Procaine HCL – laboratory reagent.
Market & Regulations
- EU & UK Ireland: permitted under REACH, requires SDS and CLP labelling.
- Canada & Australia: regulated under WHMIS and Safe Work Australia.
- USA: covered by OSHA Hazard Communication Standard.
➡ PubChem – Benzocaine
➡ ChemSpider – Benzocaine
➡ NIST WebBook – Benzocaine
➡ ChEBI – Benzocaine
➡ ECHA – Substance Info Benzocaine
Experiments & Tips
🧪 Lab exercise: Recrystallise benzocaine from ethanol and compare melting points before and after purification.
💡 Fact: Benzocaine was first synthesised in 1890 and became a model ester-type anesthetic long before lidocaine.
💡 Tip: Choose fluffy benzocaine for fast dissolution, mesh benzocaine for controlled particle size in analytical work.
Summary
Benzocaine (CAS: 94-09-7) is a versatile crystalline reagent used in analytical chemistry, pharmacological R&D and education.
CristalChem provides high-purity benzocaine fluffy & mesh powders with safe worldwide delivery and complete documentation.
➡ Benzocaine Fluffy & Mesh Powder – buy now at CristalChem
Chemical Research Writer at CristalChem Academy. Passionate about chemistry, R&D, and turning laboratory insights into global wellness and industrial innovations.