Caffeine Anhydrous – Research Reagent

Introduction

Caffeine anhydrous (CAS: 58-08-2) is a crystalline xanthine alkaloid widely used in laboratory research as a model stimulant compound. While most people know caffeine as the energy booster in coffee, in research it plays a crucial role in analytical chemistry, spectroscopy, and educational experiments.

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Properties

ParameterValue
FormulaC8H10N4O2
Molecular weight194.19 g/mol
CAS58-08-2
Melting point235–238 °C
AppearanceWhite crystalline powder
SolubilitySoluble in water and ethanol

Laboratory Applications


Experiments & Tips

🧪 Classic experiment: Compare melting points of crude caffeine extracted from tea leaves vs. pure anhydrous caffeine.
💡 Fact: Due to its consistent crystals, caffeine is often used in NMR calibration.
💡 Tip: Store sealed and dry – caffeine easily absorbs moisture, which alters weighing accuracy.


External links

➡ PubChem – Caffeine
➡ ChemSpider – Caffeine
➡ NIST WebBook – Caffeine
➡ ChEBI – Caffeine
➡ ECHA – Substance Info Caffeine

CristalChem Academy – R&D & Wellness Content Specialist at  |  + posts

Chemical Research Writer at CristalChem Academy. Passionate about chemistry, R&D, and turning laboratory insights into global wellness and industrial innovations.