Levamisole Hydrochloride (Levamisole HCl) is a dependable research reagent used in biochemical, veterinary and analytical work. Because accuracy and safety matter, this guide shows—in plain language—how to check purity, how to read COA/SDS, and how to keep your lab compliant with REACH/CLP. In addition, you will find clear steps, links to authority sources, and ready-to-use checklists.

🧪 Why Purity Verification Matters
High purity gives reliable results. Therefore, labs verify each batch before use. When Levamisole HCl meets 99.9% purity, methods run smoothly, repeat data improves, and waste goes down. Moreover, correct documentation supports customs clearance and internal audits. As a result, projects move faster and safer.
Many sellers promise quality; however, only a transparent COA (Certificate of Analysis) and a complete SDS (Safety Data Sheet) actually prove it. CristalChem tests every lot by HPLC and IR. We also include the batch number and QR verification so that your team can confirm the data instantly.
🔬 Laboratory Verification — Step by Step
Use a simple sequence. Because it is easy to follow, teams adopt it quickly and keep it in SOPs.
- Visual check: white, uniform crystals; no dust clumps. If you see changes, stop and log it.
- Solubility test: dissolve a small portion in water (20 °C). A clear solution confirms identity. Otherwise, review storage.
- Melting point: confirm 226–228 °C. If the value drifts, repeat the run and check the instrument.
- IR identity: compare the pattern with your reference file. Because identity matters most, save the spectrum in LIMS.
- HPLC purity: match retention time with the control and record purity (target ≥ 99.9%).
- Moisture (LOD): keep it < 0.2%. Then reseal the bag to limit humidity.
💡 Reference sources you can trust
Always cross-check with public databases. For quick validation, see the PubChem entry (Levamisole HCl) and the ECHA substance page. In addition, compare purity logic with these CristalChem resources: Verify Benzocaine Purity and Phenacetin Market Outlook.
⚙️ COA and SDS — What to check first
Start with the COA. It should list the CAS (16595-80-5), batch ID, purity, methods (HPLC/IR), and the analyst’s signoff. Next, read the SDS. It explains hazards, storage and transport rules. Because audits look for gaps, keep both files attached to the LIMS record.
📘 SDS quick checklist
- Section 2: hazard class and lab PPE.
- Section 7: handling and storage (dry, sealed, room temp).
- Section 9: properties: melting point, pH (1% = 3.5–5.0), solubility.
- Section 14: shipping class and UN notes.
- Section 16: REACH/CLP updates and references.
Need a refresher? Read our step guide: Safety Data Sheet — How to Read & Apply in R&D.
🌍 Compliance & Logistics — Keep it simple
CristalChem runs a compliance-first model. Therefore, each shipment includes printed COA and SDS. We also label every unit to match REACH/CLP. Furthermore, we deliver under DDP, so customs is already cleared. As a result, EU/UK labs get parcels in 1–3 business days, while USA/Canada and Asia-Pacific receive them in 3–6 days. For trade context, compare: China Legal & Safety Risks and Procaine HCl Global Supply.
🔬 Analytical Standards — Summary table
| Parameter | Specification | Method |
|---|---|---|
| Purity (HPLC) | ≥ 99.9% | USP 621 |
| Melting point | 226–228 °C | Capillary |
| Loss on drying | < 0.2% | Gravimetric |
| Identification | IR match | ATR-FTIR |
| pH (1% sol.) | 3.5–5.0 | pH meter |
🧩 Typical research uses
Because Levamisole HCl dissolves easily and behaves predictably, labs use it to calibrate chromatography and to build simple immunology models. In addition, veterinary and aquarium projects apply it in parasite studies (R&D only). For related reading, see: Levamisole HCl — Aquarium Industry, Lidocaine vs Lidocaine HCl and Benzocaine vs Benzocaine HCl.
🛒 CristalChem Reagents — fast, documented, door-to-door
Choose a pack size and check live lead times in your cart. Because we ship DDP, delivery stays simple and predictable.
- Levamisole HCl — Reagent Grade 99.9% (category)
- Benzocaine 99.9% — Analytical Powder
- Lidocaine HCl — Crystalline
- Procaine HCl — Reagent Grade
- Boric Acid — Flakes & Chunks
💬 Related Reading / Also Read
- How to Verify Benzocaine Purity
- Benzocaine vs Lidocaine — Which to Choose?
- What Is Lidocaine HCl Powder?
- Where to Buy Procaine HCl
- Phenacetin — Market Outlook
📚 External references
⚠️ Disclaimer: All information provided in this article is intended solely for scientific, educational and research purposes! The data, specifications and analytical notes come from laboratory literature and internal R&D testing. CristalChem does not guarantee completeness or absolute accuracy — please verify details before use in your own research environment. All reagents are strictly for laboratory and R&D applications only. Not for human or veterinary use!
Chemical Research Writer at CristalChem Academy. Passionate about chemistry, R&D, and turning laboratory insights into global wellness and industrial innovations.